CV
Education
University of Florida
2018-2022
PhD in Microbiology
Tulane University
2013-2017
BS in Cellular & Molecular Biology and Computer Science; Minor in Chemistry
Research Experience
Washington University in St. Louis
Mentor: Dr. Gautam Dantas
- Leveraging long read sequencing approaches to interrogate the phylogenomics and mobilome of multidrug resistant organisms in patients and community-dwellers in Pakistan
University of Florida
2018-2022
Mentor: Dr. Tony Romeo, PhD
- Examining Post-Transcriptional Regulation of Acid Stress Survival in E. coli
Tulane University
2015-2017
Mentor: Dr. Ramgopal Mettu, PhD
- Constructed a robust and generic machine learning pipeline to predict post translational modification sites of proteins via class imbalance methods
Post transcriptional Modification Prediction
2015-2016
Mentor: Dr. Chastain Anderson, PhD
- Mined comments about E-Cig flavors and used machine learning based methods to analyze the sentiment of the comments to determine the popularity of flavors which pose health risks when consumed inappropriately
Sentiment Analysis of E. Cig flavors and possible health implications
2014-2017
Mentor: Dr. Janarthanan Jayawickramarajah, PhD
- Member of a team working on micro RNA activated delivery system.
- Trained in DNA origami design, Cell culture, HPLC, and UV-Spec
Genia (A Roche Company)
2016 (Summer Internship)
- Ran experimental tests to optimize function of Nanopore sequencing chips through applying various crowding reagents, purification protocols, and cleaning protocols
- Learned to operate and debug Genia sequencing chips via Bash and Python
- Analyzed sequenced data for predicting extremely rare events
- Analyzed experimental data to determine event causes and recommended preventative measures
Fellowships & Awards
- T32 DK077653 Pediatric Gastroenterology Research Training Program
- University of Florida Graduate School Preeminence Fellowship
Publications
Papers
2023
Pourciau C., Yakhnin H., Pannuri A., Gorelik M.G., Romeo T., Babitzke P. (2023) CsrA Coordinates the Expression of Ribosome Hibernation and Anti-s Factor Proteins, Manuscript in Preparation
Gorelik M.G., Yakhnin H., Pannuri A., Walker A.C., Pourciau C., Czyz D., Babitzke P., Romeo T. (2023) Multitier regulation of the E. coli extreme acid stress response by CsrA, Manuscript in Preparation
Gorelik M.G., Gorelik A.J., Ridout K.K., Nimarko A., Peisch V., Kuramkote S.R., Low M., Pan T., Singh S., Nrusimha A., Singh M. (2023) Evaluating Efficiency and Accuracy of Deep-Learning Based Approaches on Study Selection in Systematic Reviews. *Accepted at Nature Mental Health *Denotes cofirst authorship
2022
de Crécy-lagard V., Amorin de Hegedus R., Arighi C., Babor J., Bateman A., Blaby I., Blaby-Haas C., Bridge A.J., Burley S.K., Cleveland S., Colwell L.J., Conesa A., Dallago C., Danchin A., de Waard A., Deutschbauer A., Dias R., Ding Y., Fang G., Friedberg I., Gerlt J., Goldford J., Gorelik M.G., Gyori B.M., Henry C., Hutinet G., Jaroch M., Karp P.D., Kondratova L., Lu Z., Marchler-Bauer A., Martin M., McWhite C., Moghe G.D., Monaghan P., Morgat A., Mungall C.J., Natale D.A., Nelson W.C., O’Donoghue S., Orengo C., O’Toole K.H., Radivojac P., Reed C., Roberts R.J., Rodionov D., Rodionova I.A., Rudolf J.D., Saleh L., Sheynkman G., Thibaud-Nissen F., Thomas P.D., Uetz P., Vallenet D., Carter E.W., Weigele P.R., Wood V., Wood-Charlson E.M., Xu J. (2022) A roadmap for the functional annotation of protein families: a community perspective, Database, doi: https://doi.org/10.1093/database/baac062
2021
Nimarko A.F., Gorelik A.J., Carta K.E., Gorelik M.G., Singh M.K. (2021) Neural Correlates of Reward Processing Distinguish Healthy Youth at Familial Risk for Bipolar Disorder from Youth at Familial Risk for Major Depressive Disorder, Translational Psychiatry doi: https://doi.org/10.1038/s41398-022-01800-9
2020
Pourciau C., Lai Y., Gorelik M.G., Babitzke P., Romeo T. “Diverse Mechanisms and Circuitry for Global Regulation by the RNA-Binding Protein CsrA.” Frontiers in Microbiology 11 (2020). https://doi.org/10.3389/fmicb.2020.601352
Gorelik Mark G., Gorelik Aaron J., Kathryn K. Ridout, Akua F. Nimarko, Virginia Peisch, Shamanth R. Kuramkote, Michelle Low, et al. “Applying Machine Learning to Increase Efficiency and Accuracy of Meta-Analytic Review.” Bioarxiv, 2020. https://doi.org/10.1101/2020.10.06.314245
Posters
2023
Pourciau C., Yakhnin H., Pannuri A., Gorelik M.G., Romeo T., Babitzke P. (2023) CsrA Coordinates the Expression of Ribosome Hibernation and Anti-s Factor Proteins, RNA 2023
2022
Singh M., Gorelik A.J., Gorelik M.G., Chang K., Gotlib I., Reiss A., Nimarko A., “The Intriguing Role of Thalamic Structure and Function in Youth With and at Familial Risk for Bipolar Disorder”, Biological Psychiatry, 2022
2021
Singh M., Gorelik A.J., Carta K., Gorelik M.G., Chang K., Bruno J., Nimarko A., “Thalamic Structure and Function In Youth with and at Familial Risk for Bipolar Disorder”, ISCTM, 2021
Gorelik M.G., Pannuri A., Pourciau C., Babitzke P., and Romeo T., “CsrA Regulation of the extreme acid stress response in Escherichia coli” World Microbe Forum, 2021
2019
Gorelik Mark G., Archana Pannuri, Christine Pourciau, Paul Babitzke, and Tony Romeo. “Transcriptomic Profiles of CsrA::kan Truncation vs. ΔCsrA Strains of Escherichia coli Suggests Novel and More Nuanced Impacts of the Global Regulatory Protein CsrA” ASM Poster, 2020.
Mentored Posters
2021 Wong Samantha, Mark G. Gorelik, Christine Pourciau, Joanne Lai, and Tony Romeo “Bioinformatic analysis of the correlation between the Csr system and the fim, csg and, pga operons regulation of adhesion and biofilm formation in members of the human microbiome”
Groso Christine M., Mark G. Gorelik, Christine Pourciau, Joanne Lai, and Tony Romeo “Bioinformatic analysis of the correlation between the carbon storage regulator system and extreme acid resistance systems in members of the human microbiome”
2020
Bhargava Rohan, Mark G. Gorelik, Alyssa C. Walker, Tony Romeo, Daniel M. Czyz. “Identifying butyrogenic bacteria in the human microbiome. National Institute of Antimicrobial Resistance Research and Education Knowledge Exchange Virtual Poster Session”. Abstract/Talk/Poster. July 30, 2020. First place award in Systems Approaches to Manage Antimicrobial Resistance Session
2019
Whitehead Russel, Mark Gorelik, Christine Pourciau, Archana Pannuri, and Tony Romeo. “Global suppression of a global regulatory defect: Transcriptomics analysis to understand how NusE/RpsJ evolution suppresses the growth defect caused by csrA deletion.” Poster, 2019
Conferences & Meetings
ASM Microbe 2019
Leadership & Service
2018
- UF ASM Chapter: Helped run science outreach for local schools to expose them to biology and relevant career paths
2016
- BEAST Outreach: Helped run science outreach for disadvantaged students to expose them to biology and relevant career paths
- Secretary for BEAST (Tulane ASBMB chapter)
- Tulane Jewish Leaders
- Executive Board Member of the Cookies and Code
- President of Tulane’s ACS chapter
2015
- BEAST Outreach: Helped run science outreach for disadvantaged students to expose them to biology and relevant career paths
- Member of Tulane Jewish Leaders
2014
- BEAST Outreach: Helped run science outreach for disadvantaged students to expose them to biology and relevant career paths
2013
- Tulane Outreach: Helped construct houses for those affected by Katrina in the 9th Ward
Teaching & Mentorship
UF
- Microbiology Lab for majors (MCB 3020) - Developed a curriculum focused on teaching students the concepts and programming behind data analysis, data visualization, and the microbiome
- Microbiology Lab (MCB 3000)
- Microbiology Lab (MCB 2000)